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MicroRNA-182 targets SMAD7 to potentiate TGFβ-induced epithelial-mesenchymal transition and metastasis of cancer cells

The transforming growth factor β (TGFβ) pathway plays critical roles during cancer cell epithelial-mesenchymal transition (EMT) and metastasis. SMAD7 is both a transcriptional target and a negative regulator of TGFβ signalling, thus mediating a negative feedback loop that may potentially restrain TG...

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Detalles Bibliográficos
Autores principales:	Yu, Jingyi, Lei, Rong, Zhuang, Xueqian, Li, Xiaoxun, Li, Gang, Lev, Sima, Segura, Miguel F., Zhang, Xue, Hu, Guohong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187443/ https://www.ncbi.nlm.nih.gov/pubmed/27996004 http://dx.doi.org/10.1038/ncomms13884

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