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Glutathione Peroxidase-1 Suppresses the Unfolded Protein Response upon Cigarette Smoke Exposure

Oxidative stress provokes endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR) in the lungs of chronic obstructive pulmonary (COPD) subjects. The antioxidant, glutathione peroxidase-1 (GPx-1), counters oxidative stress induced by cigarette smoke exposure. Here, we investigate wh...

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Detalles Bibliográficos
Autores principales:	Geraghty, Patrick, Baumlin, Nathalie, Salathe, Matthias A., Foronjy, Robert F., D'Armiento, Jeanine M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187475/ https://www.ncbi.nlm.nih.gov/pubmed/28070146 http://dx.doi.org/10.1155/2016/9461289

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