Endothelial-specific inhibition of NF-κB enhances functional haematopoiesis

Haematopoietic stem cells (HSCs) reside in distinct niches within the bone marrow (BM) microenvironment, comprised of endothelial cells (ECs) and tightly associated perivascular constituents that regulate haematopoiesis through the expression of paracrine factors. Here we report that the canonical N...

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Detalles Bibliográficos
Autores principales: Poulos, Michael G., Ramalingam, Pradeep, Gutkin, Michael C., Kleppe, Maria, Ginsberg, Michael, Crowley, Michael J. P., Elemento, Olivier, Levine, Ross L., Rafii, Shahin, Kitajewski, Jan, Greenblatt, Matthew B., Shim, Jae-Hyuck, Butler, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187502/
https://www.ncbi.nlm.nih.gov/pubmed/28000664
http://dx.doi.org/10.1038/ncomms13829

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