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Silymarin Activates c-AMP Phosphodiesterase and Stimulates Insulin Secretion in a Glucose-Dependent Manner in HIT-T15 Cells

Silymarin (SIL) is a flavonoid extracted from milk thistle seed that has been reported to decrease hyperglycemia in people with type 2 diabetes (T2D). However, it is not known whether SIL has direct secretory effects on β-cells. Using the β-cell line HIT-T15, SIL was shown to decrease intracellular...

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Detalles Bibliográficos
Autores principales: Meng, Ran, Mahadevan, Jana, Oseid, Elizabeth, Vallerie, Sara, Robertson, R. Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187545/
https://www.ncbi.nlm.nih.gov/pubmed/27973458
http://dx.doi.org/10.3390/antiox5040047

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