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Enhanced Autophagy in Polycystic Kidneys of AQP11 Null Mice

Aquaporin-11 (AQP11) is an intracellular water channel expressed at the endoplasmic reticulum (ER) of the proximal tubule. Its gene disruption in mice leads to intracellular vacuole formation at one week and the subsequent development of polycystic kidneys by three weeks. As the damaged proximal tub...

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Detalles Bibliográficos
Autores principales:	Tanaka, Yasuko, Watari, Mayumi, Saito, Tatsuya, Morishita, Yoshiyuki, Ishibashi, Kenichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187793/ https://www.ncbi.nlm.nih.gov/pubmed/27916883 http://dx.doi.org/10.3390/ijms17121993

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