Metformin Inhibits TGF-β1-Induced Epithelial-to-Mesenchymal Transition via PKM2 Relative-mTOR/p70s6k Signaling Pathway in Cervical Carcinoma Cells

Background: Epithelial-to-mesenchymal transition (EMT) plays a prominent role in tumorigenesis. Metformin exerts antitumorigenic effects in various cancers. This study investigated the mechanisms of metformin in TGF-β1-induced Epithelial-to-mesenchymal transition (EMT) in cervical carcinoma cells. M...

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Detalles Bibliográficos
Autores principales: Cheng, Keyan, Hao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187800/
https://www.ncbi.nlm.nih.gov/pubmed/27916907
http://dx.doi.org/10.3390/ijms17122000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187800/
https://www.ncbi.nlm.nih.gov/pubmed/27916907
http://dx.doi.org/10.3390/ijms17122000

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