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The Impact of CXCR4 Blockade on the Survival of Rat Brain Cortical Neurons

Background: Chemokine receptor type 4 (CXCR4) plays a role in neuronal survival/cell repair and also contributes to the progression of cancer and neurodegenerative diseases. Chemokine ligand 12 (CXCL12) binds to CXCR4. In this study, we have investigated whether CXCR4 blockade by AMD3100 (a CXCR4 an...

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Detalles Bibliográficos
Autores principales: Merino, José Joaquín, Garcimartín, Alba, López-Oliva, María Elvira, Benedí, Juana, González, María Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187805/
https://www.ncbi.nlm.nih.gov/pubmed/27916896
http://dx.doi.org/10.3390/ijms17122005

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