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TP53/MicroRNA Interplay in Hepatocellular Carcinoma

The role of microRNAs as oncogenes and tumor suppressor genes has emerged in several cancers, including hepatocellular carcinoma (HCC). The pivotal tumor suppressive role of p53-axis is indicated by the presence of inactivating mutations in TP53 gene in nearly all cancers. A close interaction betwee...

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Detalles Bibliográficos
Autores principales: Pollutri, Daniela, Gramantieri, Laura, Bolondi, Luigi, Fornari, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187829/
https://www.ncbi.nlm.nih.gov/pubmed/27918441
http://dx.doi.org/10.3390/ijms17122029