Pathophysiology of Non Alcoholic Fatty Liver Disease

The physiopathology of fatty liver and metabolic syndrome are influenced by diet, life style and inflammation, which have a major impact on the severity of the clinicopathologic outcome of non-alcoholic fatty liver disease. A short comprehensive review is provided on current knowledge of the pathoph...

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Detalles Bibliográficos
Autores principales: Petta, Salvatore, Gastaldelli, Amalia, Rebelos, Eleni, Bugianesi, Elisabetta, Messa, Piergiorgio, Miele, Luca, Svegliati-Baroni, Gianluca, Valenti, Luca, Bonino, Ferruccio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187882/
https://www.ncbi.nlm.nih.gov/pubmed/27973438
http://dx.doi.org/10.3390/ijms17122082
Descripción
Sumario:The physiopathology of fatty liver and metabolic syndrome are influenced by diet, life style and inflammation, which have a major impact on the severity of the clinicopathologic outcome of non-alcoholic fatty liver disease. A short comprehensive review is provided on current knowledge of the pathophysiological interplay among major circulating effectors/mediators of fatty liver, such as circulating lipids, mediators released by adipose, muscle and liver tissues and pancreatic and gut hormones in relation to diet, exercise and inflammation.

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