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Modulation of GLO1 Expression Affects Malignant Properties of Cells

The energy metabolism of most tumor cells relies on aerobic glycolysis (Warburg effect) characterized by an increased glycolytic flux that is accompanied by the increased formation of the cytotoxic metabolite methylglyoxal (MGO). Consequently, the rate of detoxification of this reactive glycolytic b...

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Detalles Bibliográficos
Autores principales:	Hutschenreuther, Antje, Bigl, Marina, Hemdan, Nasr Y. A., Debebe, Tewodros, Gaunitz, Frank, Birkenmeier, Gerd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187933/ https://www.ncbi.nlm.nih.gov/pubmed/27999356 http://dx.doi.org/10.3390/ijms17122133

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