Genetic Analysis of Human Chymotrypsin-Like Elastases 3A and 3B (CELA3A and CELA3B) to Assess the Role of Complex Formation between Proelastases and Procarboxypeptidases in Chronic Pancreatitis

Human chymotrypsin-like elastases 3A and 3B (CELA3A and CELA3B) are the products of gene duplication and share 92% identity in their primary structure. CELA3B forms stable complexes with procarboxypeptidases A1 and A2 whereas CELA3A binds poorly due to the evolutionary substitution of Ala241 with Gl...

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Detalles Bibliográficos
Autores principales: Párniczky, Andrea, Hegyi, Eszter, Tóth, Anna Zsófia, Szücs, Ákos, Szentesi, Andrea, Vincze, Áron, Izbéki, Ferenc, Németh, Balázs Csaba, Hegyi, Péter, Sahin-Tóth, Miklós
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187948/
https://www.ncbi.nlm.nih.gov/pubmed/27999401
http://dx.doi.org/10.3390/ijms17122148

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