Highly Pathogenic Reassortant Avian Influenza A(H5N1) Virus Clade 2.3.2.1a in Poultry, Bhutan

Highly pathogenic avian influenza A(H5N1), clade 2.3.2.1a, with an H9-like polymerase basic protein 1 gene, isolated in Bhutan in 2012, replicated faster in vitro than its H5N1 parental genotype and was transmitted more efficiently in a chicken model. These properties likely help limit/eradicate out...

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Detalles Bibliográficos
Autores principales: Marinova-Petkova, Atanaska, Franks, John, Tenzin, Sangay, Dahal, Narapati, Dukpa, Kinzang, Dorjee, Jambay, Feeroz, Mohammed M., Rehg, Jerold E., Barman, Subrata, Krauss, Scott, McKenzie, Pamela, Webby, Richard J., Webster, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2016
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189144/
https://www.ncbi.nlm.nih.gov/pubmed/27584733
http://dx.doi.org/10.3201/eid2212.160611
Descripción
Sumario:Highly pathogenic avian influenza A(H5N1), clade 2.3.2.1a, with an H9-like polymerase basic protein 1 gene, isolated in Bhutan in 2012, replicated faster in vitro than its H5N1 parental genotype and was transmitted more efficiently in a chicken model. These properties likely help limit/eradicate outbreaks, combined with strict control measures.

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