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Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers
BACKGROUND: The expression of NDRG1 gene is induced by nickel, a transition metal sharing similar physical properties to cobalt. Nickel may create hypoxia-like conditions in cells and induce hypoxia-responsive genes, as does cobalt. Therefore NDRG1 is likely to be another gene induced by hypoxia. HI...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC518960/ https://www.ncbi.nlm.nih.gov/pubmed/15341671 http://dx.doi.org/10.1186/1471-2156-5-27 |