Clinical Actionability of Comprehensive Genomic Profiling for Management of Rare or Refractory Cancers

BACKGROUND. The frequency with which targeted tumor sequencing results will lead to implemented change in care is unclear. Prospective assessment of the feasibility and limitations of using genomic sequencing is critically important. METHODS. A prospective clinical study was conducted on 100 patient...

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Detalles Bibliográficos
Autores principales: Hirshfield, Kim M., Tolkunov, Denis, Zhong, Hua, Ali, Siraj M., Stein, Mark N., Murphy, Susan, Vig, Hetal, Vazquez, Alexei, Glod, John, Moss, Rebecca A., Belyi, Vladimir, Chan, Chang S., Chen, Suzie, Goodell, Lauri, Foran, David, Yelensky, Roman, Palma, Norma A., Sun, James X., Miller, Vincent A., Stephens, Philip J., Ross, Jeffrey S., Kaufman, Howard, Poplin, Elizabeth, Mehnert, Janice, Tan, Antoinette R., Bertino, Joseph R., Aisner, Joseph, DiPaola, Robert S., Rodriguez-Rodriguez, Lorna, Ganesan, Shridar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AlphaMed Press 2016
Materias:
Cancer Diagnostics and Molecular Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189630/
https://www.ncbi.nlm.nih.gov/pubmed/27566247
http://dx.doi.org/10.1634/theoncologist.2016-0049

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