Cyclosporine A Treatment Abrogates Ischemia‐Induced Neuronal Cell Death by Preserving Mitochondrial Integrity through Upregulation of the Parkinson's Disease‐Associated Protein DJ‐1

AIMS: Hypoxic‐ischemia alters mitochondrial membrane potential (Δψm), respiratory‐related enzymes, and mitochondrial DNA (mtDNA). Drugs acting on mitochondria, such as cyclosporine A (CsA), may reveal novel mitochondria‐based cell death signaling targets for stroke. Our previous studies showed that...

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Detalles Bibliográficos
Autores principales: Tajiri, Naoki, Borlongan, Cesar V., Kaneko, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189675/
https://www.ncbi.nlm.nih.gov/pubmed/27247192
http://dx.doi.org/10.1111/cns.12546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189675/
https://www.ncbi.nlm.nih.gov/pubmed/27247192
http://dx.doi.org/10.1111/cns.12546

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