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B-Raf specific antibody responses in melanoma patients

BACKGROUND: Mutations of the BRAF gene are the most common genetic alteration in melanoma. Moreover, BRAF mutations are already present in benign nevi. Being overexpressed and mutated, B-Raf is a potential target for the immune system and as this mutation seems to be an early event, a humoral immune...

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Detalles Bibliográficos
Autores principales: Fensterle, Joachim, Becker, Jürgen C, Potapenko, Tamara, Heimbach, Veronika, Vetter, Claudia S, Bröcker, Eva B, Rapp, Ulf R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC518968/
https://www.ncbi.nlm.nih.gov/pubmed/15361259
http://dx.doi.org/10.1186/1471-2407-4-62