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B-Raf specific antibody responses in melanoma patients
BACKGROUND: Mutations of the BRAF gene are the most common genetic alteration in melanoma. Moreover, BRAF mutations are already present in benign nevi. Being overexpressed and mutated, B-Raf is a potential target for the immune system and as this mutation seems to be an early event, a humoral immune...
Autores principales: | Fensterle, Joachim, Becker, Jürgen C, Potapenko, Tamara, Heimbach, Veronika, Vetter, Claudia S, Bröcker, Eva B, Rapp, Ulf R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC518968/ https://www.ncbi.nlm.nih.gov/pubmed/15361259 http://dx.doi.org/10.1186/1471-2407-4-62 |
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