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Effect of the Polymorphism of Folylpolyglutamate Synthetase on Treatment of High-Dose Methotrexate in Pediatric Patients with Acute Lymphocytic Leukemia

BACKGROUND: The aim of this study was to investigate the association of the polymorphism of folylpolyglutamate synthetase (FPGS) with the dynamic plasma concentration of methotrexate (MTX) in pediatric patients with acute lymphocytic leukemia (ALL), as well as the prognosis. MATERIAL/METHODS: 57 ALL...

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Detalles Bibliográficos
Autores principales:	Huang, Zhen, Tong, Hong-Fei, Li, Yuan, Qian, Jiang-Chao, Wang, Ju-Xiang, Wang, Zhe, Ruan, Ji-Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2016
Materias:	Clinical Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189722/ https://www.ncbi.nlm.nih.gov/pubmed/27987364 http://dx.doi.org/10.12659/MSM.899021

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