Temporal variability of glucocorticoid receptor activity is functionally important for the therapeutic action of fluoxetine in the hippocampus

Previous studies have shown inconsistent results regarding the actions of antidepressants on glucocorticoid receptor (GR) signalling. To resolve these inconsistencies, we used a lentiviral-based reporter system to directly monitor rat hippocampal GR activity during stress adaptation. Temporal GR act...

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Detalles Bibliográficos
Autores principales: Lee, M-S, Kim, Y-H, Park, W-S, Park, O-K, Kwon, S-H, Hong, K S, Rhim, H, Shim, I, Morita, K, Wong, D L, Patel, P D, Lyons, D M, Schatzberg, A F, Her, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189925/
https://www.ncbi.nlm.nih.gov/pubmed/25330740
http://dx.doi.org/10.1038/mp.2014.137

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