Cargando…

Mutational Profile of Metastatic Breast Cancers: A Retrospective Analysis

BACKGROUND: Major advances have been achieved in the characterization of early breast cancer (eBC) genomic profiles. Metastatic breast cancer (mBC) is associated with poor outcomes, yet limited information is available on the genomic profile of this disease. This study aims to decipher mutational pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lefebvre, Celine, Bachelot, Thomas, Filleron, Thomas, Pedrero, Marion, Campone, Mario, Soria, Jean-Charles, Massard, Christophe, Lévy, Christelle, Arnedos, Monica, Lacroix-Triki, Magali, Garrabey, Julie, Boursin, Yannick, Deloger, Marc, Fu, Yu, Commo, Frédéric, Scott, Véronique, Lacroix, Ludovic, Dieci, Maria Vittoria, Kamal, Maud, Diéras, Véronique, Gonçalves, Anthony, Ferrerro, Jean-Marc, Romieu, Gilles, Vanlemmens, Laurence, Mouret Reynier, Marie-Ange, Théry, Jean-Christophe, Le Du, Fanny, Guiu, Séverine, Dalenc, Florence, Clapisson, Gilles, Bonnefoi, Hervé, Jimenez, Marta, Le Tourneau, Christophe, André, Fabrice
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189935/ https://www.ncbi.nlm.nih.gov/pubmed/28027327 http://dx.doi.org/10.1371/journal.pmed.1002201

Ejemplares similares

Efficacy of trastuzumab emtansine (T-DM1) and lapatinib after dual HER2 inhibition with trastuzumab and pertuzumab in patient with metastatic breast cancer: Retrospective data from a French multicenter real-life cohort
por: Moinard-Butot, Fabien, et al.
Publicado: (2022)

Fuzzy logic selection as a new reliable tool to identify molecular grade signatures in breast cancer – the INNODIAG study
por: Kempowsky-Hamon, Tatiana, et al.
Publicado: (2015)

Lymphopenia combined with low TCR diversity (divpenia) predicts poor overall survival in metastatic breast cancer patients
por: Manuel, Manuarii, et al.
Publicado: (2012)

A Phase I, Dose-Escalation Trial of Pazopanib in Combination with Cisplatin in Patients with Advanced Solid Tumors: A UNICANCER Study
por: Diéras, Véronique, et al.
Publicado: (2016)

Comparison of Variable Selection Methods for Time-to-Event Data in High-Dimensional Settings
por: Gilhodes, Julia, et al.
Publicado: (2020)

Impact of age at diagnosis of metastatic breast cancer on overall survival in the real-life ESME metastatic breast cancer cohort
por: Frank, Sophie, et al.
Publicado: (2020)

Patient-reported tolerability of adverse events in phase 1 trials
por: Henon, Clémence, et al.
Publicado: (2017)

Real-World Impact of Adjuvant Anti-HER2 Treatment on Characteristics and Outcomes of Women With HER2-Positive Metastatic Breast Cancer in the ESME Program
por: Le Du, Fanny, et al.
Publicado: (2023)

Long-Term Results with Everolimus in Advanced Hormone Receptor Positive Breast Cancer in a Multicenter National Real-World Observational Study
por: François-Martin, Hélène, et al.
Publicado: (2023)

Longitudinal serum metabolomics evaluation of trastuzumab and everolimus combination as pre-operative treatment for HER-2 positive breast cancer patients
por: Jobard, Elodie, et al.
Publicado: (2017)

Real-world evidence of the management and prognosis of young women (⩽40 years) with de novo metastatic breast cancer
por: Mallet, Amélie, et al.
Publicado: (2022)

Trastuzumab deruxtecan in metastatic breast cancer with variable HER2 expression: the phase 2 DAISY trial
por: Mosele, Fernanda, et al.
Publicado: (2023)

New advances in DPYD genotype and risk of severe toxicity under capecitabine
por: Etienne-Grimaldi, Marie-Christine, et al.
Publicado: (2017)

Contribution of Reliable Chromatographic Data in QSAR for Modelling Bisphenol Transport across the Human Placenta Barrier
por: Gély, Clémence A., et al.
Publicado: (2023)

Impact of breast cancer molecular subtypes on the incidence, kinetics and prognosis of central nervous system metastases in a large multicentre real-life cohort
por: Darlix, Amélie, et al.
Publicado: (2019)

Untargeted Metabolomics Approach Using UHPLC-HRMS to Unravel the Impact of Fermentation on Color and Phenolic Composition of Rosé Wines
por: Leborgne, Cécile, et al.
Publicado: (2023)

Inhibitory activity spectrum of reuterin produced by Lactobacillus reuteri against intestinal bacteria
por: Cleusix, Valentine, et al.
Publicado: (2007)

Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties
por: de Medina, Philippe, et al.
Publicado: (2013)

Predictive factors of 5-year relapse-free survival in HR+/HER2- breast cancer patients treated with neoadjuvant endocrine therapy: pooled analysis of two phase 2 trials
por: Lerebours, Florence, et al.
Publicado: (2020)

Combinations of targeted therapies in human cancers
por: Decaudin, Didier, et al.
Publicado: (2016)

Pembrolizumab in cervical cancer: latest evidence and clinical usefulness
por: Borcoman, Edith, et al.
Publicado: (2017)

Keynote-158 study, FDA granted accelerated approval of pembrolizumab for the treatment of patients with advanced PD-L1-positive cervical cancer
por: Borcoman, Edith, et al.
Publicado: (2020)

Portrait of Ependymoma Recurrence in Children: Biomarkers of Tumor Progression Identified by Dual-Color Microarray-Based Gene Expression Analysis
por: Peyre, Matthieu, et al.
Publicado: (2010)

Comparison of Management and Outcomes in ERBB2-Low vs ERBB2-Zero Metastatic Breast Cancer in France
por: de Calbiac, Ombline, et al.
Publicado: (2022)

Unlikely association of nephrectomy post-mRCC with anti-VEGF-induced renal TMA
por: Izzedine, Hassane, et al.
Publicado: (2011)

Farnesyl-transferase inhibitor R115,777 enhances tamoxifen inhibition of MCF-7 cell growth through estrogen receptor dependent and independent pathways
por: Dalenc, Florence, et al.
Publicado: (2005)

Efficacy of taxanes rechallenge in first-line treatment of early metastatic relapse of patients with HER2-negative breast cancer previously treated with a (neo)adjuvant taxanes regimen: A multicentre retrospective observational study
por: Vasseur, Antoine, et al.
Publicado: (2022)

Beyond EGFR Targeting in SCCHN: Angiogenesis, PI3K, and Other Molecular Targets
por: Saada-Bouzid, Esma, et al.
Publicado: (2019)

Drug Development in Tissue-Agnostic Indications
por: du Rusquec, Pauline, et al.
Publicado: (2021)

Personalised cancer follow-up: risk stratification, needs assessment or both?
por: Filleron, T, et al.
Publicado: (2012)

Brain metastases from breast cancer: prognostic significance of HER-2 overexpression, effect of trastuzumab and cause of death
por: Le Scodan, Romuald, et al.
Publicado: (2011)

Coronavirus disease (COVID-19) outbreak and phase 1 trials: should we consider a specific patient management?
por: Postel-Vinay, Sophie, et al.
Publicado: (2020)

Management and outcome of male metastatic breast cancer in the national multicenter observational research program Epidemiological Strategy and Medical Economics (ESME)
por: Sirieix, Junien, et al.
Publicado: (2020)

Real-life prognosis of 5041 bone-only metastatic breast cancer patients in the multicenter national observational ESME program
por: Bertho, Marion, et al.
Publicado: (2021)

Plasmon-Induced Nanolocalized Reduction of Diazonium Salts
por: Nguyen, Van-Quynh, et al.
Publicado: (2017)

RhoB modifies estrogen responses in breast cancer cells by influencing expression of the estrogen receptor
por: Médale-Giamarchi, Claire, et al.
Publicado: (2013)

Safety Results and Analysis of Eribulin Efficacy according to Previous Microtubules-Inhibitors Sensitivity in the French Prospective Expanded Access Program for Heavily Pre-treated Metastatic Breast Cancer
por: Sabatier, Renaud, et al.
Publicado: (2018)

Sunitinib: a novel tyrosine kinase inhibitor. A brief review of its therapeutic potential in the treatment of renal carcinoma and gastrointestinal stromal tumors (GIST)
por: Le Tourneau, Christophe, et al.
Publicado: (2007)

Hyperprogression under Immunotherapy
por: Frelaut, Maxime, et al.
Publicado: (2019)

Paradigm Change in First-Line Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma
por: Borcoman, Edith, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_vclqoq4gmdlq89k4f9nm50um7f