Within Host Evolution Selects for a Dominant Genotype of Mycobacterium tuberculosis while T Cells Increase Pathogen Genetic Diversity

Molecular epidemiological assessments, drug treatment optimization, and development of immunological interventions all depend on understanding pathogen adaptation and genetic variation, which differ for specific pathogens. Mycobacterium tuberculosis is an exceptionally successful human pathogen, yet...

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Detalles Bibliográficos
Autores principales: Copin, Richard, Wang, Xueying, Louie, Eddie, Escuyer, Vincent, Coscolla, Mireia, Gagneux, Sebastien, Palmer, Guy H., Ernst, Joel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189959/
https://www.ncbi.nlm.nih.gov/pubmed/27973588
http://dx.doi.org/10.1371/journal.ppat.1006111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189959/
https://www.ncbi.nlm.nih.gov/pubmed/27973588
http://dx.doi.org/10.1371/journal.ppat.1006111

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