Definitive activation of endogenous antitumor immunity by repetitive cycles of cyclophosphamide with interspersed Toll-like receptor agonists

Many cancers both evoke and subvert endogenous anti-tumor immunity. However, immunosuppression can be therapeutically reversed in subsets of cancer patients by treatments such as checkpoint inhibitors or Toll-like receptor agonists (TLRa). Moreover, chemotherapy can leukodeplete immunosuppressive ho...

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Detalles Bibliográficos
Autores principales: Manrique, Soraya Zorro, Dominguez, Ana L., Mirza, Noweeda, Spencer, Christopher D., Bradley, Judy M., Finke, James H., Lee, James J., Pease, Larry R., Gendler, Sandra J., Cohen, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189997/
https://www.ncbi.nlm.nih.gov/pubmed/27341020
http://dx.doi.org/10.18632/oncotarget.10190

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