Tailored chemokine receptor modification improves homing of adoptive therapy T cells in a spontaneous tumor model

In recent years, tumor Adoptive Cell Therapy (ACT), using administration of ex vivo-enhanced T cells from the cancer patient, has become a promising therapeutic strategy. However, efficient homing of the anti-tumoral T cells to the tumor or metastatic site still remains a substantial hurdle. Yet the...

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Detalles Bibliográficos
Autores principales: Garetto, Stefano, Sardi, Claudia, Martini, Elisa, Roselli, Giuliana, Morone, Diego, Angioni, Roberta, Cianciotti, Beatrice Claudia, Trovato, Anna Elisa, Franchina, Davide Giuseppe, Castino, Giovanni Francesco, Vignali, Debora, Erreni, Marco, Marchesi, Federica, Rumio, Cristiano, Kallikourdis, Marinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190004/
https://www.ncbi.nlm.nih.gov/pubmed/27177227
http://dx.doi.org/10.18632/oncotarget.9280

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