Tunneling nanotube formation is stimulated by hypoxia in ovarian cancer cells

In this study, we demonstrated that hypoxic conditions stimulated an increase in tunneling nanotube (TNT) formation in chemoresistant ovarian cancer cells (SKOV3, C200). We found that suppressing the mTOR pathway using either everolimus or metformin led to suppression of TNT formation in vitro, veri...

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Detalles Bibliográficos
Autores principales: Desir, Snider, Dickson, Elizabeth L., Vogel, Rachel I., Thayanithy, Venugopal, Wong, Phillip, Teoh, Deanna, Geller, Melissa A., Steer, Clifford J., Subramanian, Subbaya, Lou, Emil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190014/
https://www.ncbi.nlm.nih.gov/pubmed/27223082
http://dx.doi.org/10.18632/oncotarget.9504

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