Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells

Tumorigenesis is a multistep process involving co-operation between several deregulated oncoproteins. In this study, we unravel previously unrecognized interactions and crosstalk between Pim kinases and the Notch signaling pathway, with implications for both breast and prostate cancer. We identify N...

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Detalles Bibliográficos
Autores principales: Santio, Niina M., Landor, Sebastian K.-J., Vahtera, Laura, Ylä-Pelto, Jani, Paloniemi, Elina, Imanishi, Susumu Y., Corthals, Garry, Varjosalo, Markku, Manoharan, Ganesh Babu, Uri, Asko, Lendahl, Urban, Sahlgren, Cecilia, Koskinen, Päivi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190019/
https://www.ncbi.nlm.nih.gov/pubmed/27281612
http://dx.doi.org/10.18632/oncotarget.9215

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