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Expression and functional characterization of CD33 transcript variants in human acute myeloid leukemia
With the demonstration of improved survival of some acute myeloid leukemia (AML) patients with the CD33 antibody-drug conjugate, gemtuzumab ozogamicin (GO), CD33 has been validated as a target for antigen-specific immunotherapy. Since previous studies identified a CD33 splice variant missing exon 2...
Autores principales: | Laszlo, George S., Harrington, Kimberly H., Gudgeon, Chelsea J., Beddoe, Mary E., Fitzgibbon, Matthew P., Ries, Rhonda E., Lamba, Jatinder K., McIntosh, Martin W., Meshinchi, Soheil, Walter, Roland B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190023/ https://www.ncbi.nlm.nih.gov/pubmed/27248327 http://dx.doi.org/10.18632/oncotarget.9674 |
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