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The role of WNT/β-catenin signaling pathway in melanoma epithelial-to-mesenchymal-like switching: evidences from patients-derived cell lines

Deregulations or mutations of WNT/β-catenin signaling have been associated to both tumour formation and progression. However, contradictory results concerning the role of β-catenin in human melanoma address an open question on its oncogenic nature and prognostic value in this tumour. Changes in WNT...

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Detalles Bibliográficos
Autores principales: Kovacs, Daniela, Migliano, Emilia, Muscardin, Luca, Silipo, Vitaliano, Catricalà, Caterina, Picardo, Mauro, Bellei, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190024/
https://www.ncbi.nlm.nih.gov/pubmed/27175588
http://dx.doi.org/10.18632/oncotarget.9232