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Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs

Cachexia affects the majority of cancer patients, with currently no effective treatments. Cachexia is defined by increased fatigue and loss of muscle function resulting from muscle and fat depletion. Previous studies suggest that chemotherapy may contribute to cachexia, although the causes responsib...

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Detalles Bibliográficos
Autores principales: Barreto, Rafael, Waning, David L., Gao, Hongyu, Liu, Yunlong, Zimmers, Teresa A., Bonetto, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190036/
https://www.ncbi.nlm.nih.gov/pubmed/27259276
http://dx.doi.org/10.18632/oncotarget.9779