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Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs
Cachexia affects the majority of cancer patients, with currently no effective treatments. Cachexia is defined by increased fatigue and loss of muscle function resulting from muscle and fat depletion. Previous studies suggest that chemotherapy may contribute to cachexia, although the causes responsib...
Autores principales: | Barreto, Rafael, Waning, David L., Gao, Hongyu, Liu, Yunlong, Zimmers, Teresa A., Bonetto, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190036/ https://www.ncbi.nlm.nih.gov/pubmed/27259276 http://dx.doi.org/10.18632/oncotarget.9779 |
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