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Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells

The secretion of soluble pro-angiogenic factors by tumor cells and stromal cells in the perivascular niche promotes the aggressive angiogenesis that is typical of glioblastoma (GBM). Here, we show that angiogenesis also can be promoted by a direct interaction between brain tumor cells, including tum...

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Detalles Bibliográficos
Autores principales: Burgett, Monica E., Lathia, Justin D., Roth, Patrick, Nowacki, Amy S., Galileo, Deni S., Pugacheva, Elena, Huang, Ping, Vasanji, Amit, Li, Meizhang, Byzova, Tatiana, Mikkelsen, Tom, Bao, Shideng, Rich, Jeremy N., Weller, Michael, Gladson, Candece L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190064/
https://www.ncbi.nlm.nih.gov/pubmed/27270311
http://dx.doi.org/10.18632/oncotarget.9700