MLLT11/AF1q boosts oncogenic STAT3 activity through Src-PDGFR tyrosine kinase signaling

Constitutive STAT3 activation by tyrosine phosphorylation of mutated or amplified tyrosine kinases (pYSTAT3) is critical for cancer initiation, progression, invasion, and motility of carcinoma cells. We showed that AF1q is associated with STAT3 signaling in breast cancer cells. In xenograft models,...

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Detalles Bibliográficos
Autores principales: Park, Jino, Kim, Soojin, Joh, Joongho, Remick, Scot C., Miller, Donald M., Yan, Jun, Kanaan, Zeyad, Chao, Ju-Hsien, Krem, Maxwell M., Basu, Soumit K., Hagiwara, Shotaro, Kenner, Lukas, Moriggl, Richard, Bunting, Kevin D., Tse, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190071/
https://www.ncbi.nlm.nih.gov/pubmed/27259262
http://dx.doi.org/10.18632/oncotarget.9759

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