Crucial factors of the inflammatory microenvironment (IL-1β/TNF-α/TIMP-1) promote the maintenance of the malignant hemopoietic clone of myelofibrosis: an in vitro study

Along with molecular abnormalities (mutations in JAK2, Calreticulin (CALR) and MPL genes), chronic inflammation is the major hallmark of Myelofibrosis (MF). Here, we investigated the in vitro effects of crucial factors of the inflammatory microenvironment (Interleukin (IL)-1β, Tumor Necrosis Factor...

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Detalles Bibliográficos
Autores principales: Sollazzo, Daria, Forte, Dorian, Polverelli, Nicola, Romano, Marco, Perricone, Margherita, Rossi, Lara, Ottaviani, Emanuela, Luatti, Simona, Martinelli, Giovanni, Vianelli, Nicola, Cavo, Michele, Palandri, Francesca, Catani, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190072/
https://www.ncbi.nlm.nih.gov/pubmed/27304059
http://dx.doi.org/10.18632/oncotarget.9949

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