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Reduced genomic tumor heterogeneity after neoadjuvant chemotherapy is related to favorable outcome in patients with esophageal adenocarcinoma

Neoadjuvant chemo(radio)therapy followed by surgery is the standard of care for patients with locally advanced resectable esophageal adenocarcinoma (EAC). There is increasing evidence that drug resistance might be related to genomic heterogeneity. We investigated whether genomic tumor heterogeneity...

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Detalles Bibliográficos
Autores principales:	Obulkasim, Askar, Ylstra, Bauke, van Essen, Hendrik F., Benner, Christian, Stenning, Sally, Langley, Ruth, Allum, William, Cunningham, David, Inam, Imran, Hewitt, Lindsay C., West, Nicolas P., Meijer, Gerrit A., van de Wiel, Mark A., Grabsch, Heike I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190081/ https://www.ncbi.nlm.nih.gov/pubmed/27286451 http://dx.doi.org/10.18632/oncotarget.9857

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