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Individual heritable differences result in unique cell lymphocyte receptor repertoires of naïve and antigen-experienced cells
The adaptive immune system's capability to protect the body requires a highly diverse lymphocyte antigen receptor repertoire. However, the influence of individual genetic and epigenetic differences on these repertoires is not typically measured. By leveraging the unique characteristics of B, CD...
Autores principales: | Rubelt, Florian, Bolen, Christopher R., McGuire, Helen M., Heiden, Jason A. Vander, Gadala-Maria, Daniel, Levin, Mikhail, M. Euskirchen, Ghia, Mamedov, Murad R., Swan, Gary E., Dekker, Cornelia L., Cowell, Lindsay G., Kleinstein, Steven H., Davis, Mark M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191574/ https://www.ncbi.nlm.nih.gov/pubmed/27005435 http://dx.doi.org/10.1038/ncomms11112 |
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