Expansion induced microRNA changes in bone marrow mesenchymal stromal cells reveals interplay between immune regulation and cell cycle

Mesenchymal stromal cells (MSC) are currently used in many cell based therapies. Prior to use in therapy, extensive expansion is required. We used microarray profiling to investigate expansion induced miRNA and mRNA expression changes of bone marrow MSCs (BM-MSCs) derived from old and young donors....

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Detalles Bibliográficos
Autores principales: Kilpinen, Lotta, Parmar, Amarjit, Greco, Dario, Korhonen, Matti, Lehenkari, Petri, Saavalainen, Päivi, Laitinen, Saara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191871/
https://www.ncbi.nlm.nih.gov/pubmed/27852979
http://dx.doi.org/10.18632/aging.101088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191871/
https://www.ncbi.nlm.nih.gov/pubmed/27852979
http://dx.doi.org/10.18632/aging.101088

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