Cargando…
Expansion induced microRNA changes in bone marrow mesenchymal stromal cells reveals interplay between immune regulation and cell cycle
Mesenchymal stromal cells (MSC) are currently used in many cell based therapies. Prior to use in therapy, extensive expansion is required. We used microarray profiling to investigate expansion induced miRNA and mRNA expression changes of bone marrow MSCs (BM-MSCs) derived from old and young donors....
Autores principales: | Kilpinen, Lotta, Parmar, Amarjit, Greco, Dario, Korhonen, Matti, Lehenkari, Petri, Saavalainen, Päivi, Laitinen, Saara |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191871/ https://www.ncbi.nlm.nih.gov/pubmed/27852979 http://dx.doi.org/10.18632/aging.101088 |
Ejemplares similares
-
A robust and reproducible animal serum-free culture method for clinical-grade bone marrow-derived mesenchymal stromal cells
por: Laitinen, Anita, et al.
Publicado: (2015) -
Methylome Analysis of Human Bone Marrow MSCs Reveals Extensive Age- and Culture-Induced Changes at Distal Regulatory Elements
por: Pasumarthy, Kalyan K., et al.
Publicado: (2017) -
Mesenchymal Stromal Cells and Their Extracellular Vesicles Enhance the Anti-Inflammatory Phenotype of Regulatory Macrophages by Downregulating the Production of Interleukin (IL)-23 and IL-22
por: Hyvärinen, Kati, et al.
Publicado: (2018) -
Human Mesenchymal Stromal Cell Secretome Promotes the Immunoregulatory Phenotype and Phagocytosis Activity in Human Macrophages
por: Holopainen, Minna, et al.
Publicado: (2020) -
Gene Expression Profiling of Gliadin Effects on Intestinal Epithelial Cells Suggests Novel Non-Enzymatic Functions of Pepsin and Trypsin
por: Parmar, Amarjit, et al.
Publicado: (2013)