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Mitochondrial Stress Induced p53 Attenuates HIF-1α Activity by Physical Association and Enhanced Ubiquitination

Retrograde signaling is a mechanism by which mitochondrial dysfunction is communicated to the nucleus for inducing a metabolic shift essential for cell survival. Previously we showed that partial mtDNA depletion in different cell types induced mitochondrial retrograde signaling pathway (MtRS) involv...

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Detalles Bibliográficos
Autores principales:	Chowdhury, Anindya Roy, Long, Apple, Fuchs, Serge, Rustgi, Anil, Avadhani, Narayan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192009/ https://www.ncbi.nlm.nih.gov/pubmed/27345397 http://dx.doi.org/10.1038/onc.2016.211

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