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GM-CSF signalling blockade and chemotherapeutic agents act in concert to inhibit the function of myeloid-derived suppressor cells in vitro
Immune evasion is a recently defined hallmark of cancer, and immunotherapeutic approaches that stimulate an immune response to tumours are gaining recognition. However tumours may evade the immune response and resist immune-targeted treatment by promoting an immune-suppressive environment and stimul...
Autores principales: | Gargett, Tessa, Christo, Susan N, Hercus, Timothy R, Abbas, Nazim, Singhal, Nimit, Lopez, Angel F, Brown, Michael P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192067/ https://www.ncbi.nlm.nih.gov/pubmed/28090321 http://dx.doi.org/10.1038/cti.2016.80 |
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