Combined Systems Approaches Reveal a Multistage Mode of Action of a Marine Antimicrobial Peptide against Pathogenic Escherichia coli and Its Protective Effect against Bacterial Peritonitis and Endotoxemia

A marine arenicin-3 derivative, N4, displayed potent antibacterial activity against Gram-negative bacteria, but its antibacterial mode of action remains elusive. The mechanism of action of N4 against pathogenic Escherichia coli was first researched by combined cytological and transcriptomic techniqu...

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Detalles Bibliográficos
Autores principales: Wang, Xiumin, Teng, Da, Mao, Ruoyu, Yang, Na, Hao, Ya, Wang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192121/
https://www.ncbi.nlm.nih.gov/pubmed/27795369
http://dx.doi.org/10.1128/AAC.01056-16

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