p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis

Spatiotemporal activation of RhoA and actomyosin contraction underpins cellular adhesion and division. Loss of cell–cell adhesion and chromosomal instability are cardinal events that drive tumour progression. Here, we show that p120-catenin (p120) not only controls cell–cell adhesion, but also acts...

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Detalles Bibliográficos
Autores principales: van de Ven, Robert A.H., de Groot, Jolien S., Park, Danielle, van Domselaar, Robert, de Jong, Danielle, Szuhai, Karoly, van der Wall, Elsken, Rueda, Oscar M., Ali, H. Raza, Caldas, Carlos, van Diest, Paul J., Hetzer, Martin W., Sahai, Erik, Derksen, Patrick W.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192218/
https://www.ncbi.nlm.nih.gov/pubmed/28004812
http://dx.doi.org/10.1038/ncomms13874

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