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Isolated primary tuberculosis of spleen—A rare entity in the immuno-competent patient
INTRODUCTION: Tuberculosis is a global public health concern, with 9.6 million affected individuals worldwide. Current screening and diagnostic regimes focus primarily on smear positivity, and hence, the rising numbers of Sputum negative and Extra-Pulmonary Tuberculosis has become a significant set-...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192240/ https://www.ncbi.nlm.nih.gov/pubmed/28006720 http://dx.doi.org/10.1016/j.ijscr.2016.11.038 |
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author | Kumar, Suneed Pai, Ajay G. Tungenwar, Pravin N. Bhandarwar, Ajay H. |
author_facet | Kumar, Suneed Pai, Ajay G. Tungenwar, Pravin N. Bhandarwar, Ajay H. |
author_sort | Kumar, Suneed |
collection | PubMed |
description | INTRODUCTION: Tuberculosis is a global public health concern, with 9.6 million affected individuals worldwide. Current screening and diagnostic regimes focus primarily on smear positivity, and hence, the rising numbers of Sputum negative and Extra-Pulmonary Tuberculosis has become a significant set-back to adequate diagnosis, disease notification and treatment, due to the large number of false negatives. PRESENTATION OF CASE: We hereby describe an intriguing presentation of tuberculosis – A 23 yr old lady with no comorbid illness, came to us with ten month history of on and off pyrexia, weakness and left hypochondriac pain. On evaluation, two isolated hypodense lesions in the spleen were detected. Diagnostic laparoscopy and Splenectomy were performed and histopathology revealed features of primary tubercular abscess. DISCUSSION: Commonly, abdominal visceral involvement is seen as a part of miliary tuberculosis in the immuno-compromised patient. However, in the absence of any co-morbidity and preserved immune function, this case depicts the rare possibility of primary isolated Tubercular splenic abscess in the normal healthy individual. CONCLUSION: We require a close eye and a keen sense of clinical acumen to accurately diagnose and treat smear negative and uncommon forms of Tuberculosis. Considering the growing prevalence and difficulty in disease control, there is need for greater knowledge and awareness to help mitigate the global burden of Tuberculosis. |
format | Online Article Text |
id | pubmed-5192240 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-51922402017-01-03 Isolated primary tuberculosis of spleen—A rare entity in the immuno-competent patient Kumar, Suneed Pai, Ajay G. Tungenwar, Pravin N. Bhandarwar, Ajay H. Int J Surg Case Rep Case Report INTRODUCTION: Tuberculosis is a global public health concern, with 9.6 million affected individuals worldwide. Current screening and diagnostic regimes focus primarily on smear positivity, and hence, the rising numbers of Sputum negative and Extra-Pulmonary Tuberculosis has become a significant set-back to adequate diagnosis, disease notification and treatment, due to the large number of false negatives. PRESENTATION OF CASE: We hereby describe an intriguing presentation of tuberculosis – A 23 yr old lady with no comorbid illness, came to us with ten month history of on and off pyrexia, weakness and left hypochondriac pain. On evaluation, two isolated hypodense lesions in the spleen were detected. Diagnostic laparoscopy and Splenectomy were performed and histopathology revealed features of primary tubercular abscess. DISCUSSION: Commonly, abdominal visceral involvement is seen as a part of miliary tuberculosis in the immuno-compromised patient. However, in the absence of any co-morbidity and preserved immune function, this case depicts the rare possibility of primary isolated Tubercular splenic abscess in the normal healthy individual. CONCLUSION: We require a close eye and a keen sense of clinical acumen to accurately diagnose and treat smear negative and uncommon forms of Tuberculosis. Considering the growing prevalence and difficulty in disease control, there is need for greater knowledge and awareness to help mitigate the global burden of Tuberculosis. Elsevier 2016-11-25 /pmc/articles/PMC5192240/ /pubmed/28006720 http://dx.doi.org/10.1016/j.ijscr.2016.11.038 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Kumar, Suneed Pai, Ajay G. Tungenwar, Pravin N. Bhandarwar, Ajay H. Isolated primary tuberculosis of spleen—A rare entity in the immuno-competent patient |
title | Isolated primary tuberculosis of spleen—A rare entity in the immuno-competent patient |
title_full | Isolated primary tuberculosis of spleen—A rare entity in the immuno-competent patient |
title_fullStr | Isolated primary tuberculosis of spleen—A rare entity in the immuno-competent patient |
title_full_unstemmed | Isolated primary tuberculosis of spleen—A rare entity in the immuno-competent patient |
title_short | Isolated primary tuberculosis of spleen—A rare entity in the immuno-competent patient |
title_sort | isolated primary tuberculosis of spleen—a rare entity in the immuno-competent patient |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192240/ https://www.ncbi.nlm.nih.gov/pubmed/28006720 http://dx.doi.org/10.1016/j.ijscr.2016.11.038 |
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