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Isolated primary tuberculosis of spleen—A rare entity in the immuno-competent patient

INTRODUCTION: Tuberculosis is a global public health concern, with 9.6 million affected individuals worldwide. Current screening and diagnostic regimes focus primarily on smear positivity, and hence, the rising numbers of Sputum negative and Extra-Pulmonary Tuberculosis has become a significant set-...

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Autores principales: Kumar, Suneed, Pai, Ajay G., Tungenwar, Pravin N., Bhandarwar, Ajay H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192240/
https://www.ncbi.nlm.nih.gov/pubmed/28006720
http://dx.doi.org/10.1016/j.ijscr.2016.11.038
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author Kumar, Suneed
Pai, Ajay G.
Tungenwar, Pravin N.
Bhandarwar, Ajay H.
author_facet Kumar, Suneed
Pai, Ajay G.
Tungenwar, Pravin N.
Bhandarwar, Ajay H.
author_sort Kumar, Suneed
collection PubMed
description INTRODUCTION: Tuberculosis is a global public health concern, with 9.6 million affected individuals worldwide. Current screening and diagnostic regimes focus primarily on smear positivity, and hence, the rising numbers of Sputum negative and Extra-Pulmonary Tuberculosis has become a significant set-back to adequate diagnosis, disease notification and treatment, due to the large number of false negatives. PRESENTATION OF CASE: We hereby describe an intriguing presentation of tuberculosis – A 23 yr old lady with no comorbid illness, came to us with ten month history of on and off pyrexia, weakness and left hypochondriac pain. On evaluation, two isolated hypodense lesions in the spleen were detected. Diagnostic laparoscopy and Splenectomy were performed and histopathology revealed features of primary tubercular abscess. DISCUSSION: Commonly, abdominal visceral involvement is seen as a part of miliary tuberculosis in the immuno-compromised patient. However, in the absence of any co-morbidity and preserved immune function, this case depicts the rare possibility of primary isolated Tubercular splenic abscess in the normal healthy individual. CONCLUSION: We require a close eye and a keen sense of clinical acumen to accurately diagnose and treat smear negative and uncommon forms of Tuberculosis. Considering the growing prevalence and difficulty in disease control, there is need for greater knowledge and awareness to help mitigate the global burden of Tuberculosis.
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spelling pubmed-51922402017-01-03 Isolated primary tuberculosis of spleen—A rare entity in the immuno-competent patient Kumar, Suneed Pai, Ajay G. Tungenwar, Pravin N. Bhandarwar, Ajay H. Int J Surg Case Rep Case Report INTRODUCTION: Tuberculosis is a global public health concern, with 9.6 million affected individuals worldwide. Current screening and diagnostic regimes focus primarily on smear positivity, and hence, the rising numbers of Sputum negative and Extra-Pulmonary Tuberculosis has become a significant set-back to adequate diagnosis, disease notification and treatment, due to the large number of false negatives. PRESENTATION OF CASE: We hereby describe an intriguing presentation of tuberculosis – A 23 yr old lady with no comorbid illness, came to us with ten month history of on and off pyrexia, weakness and left hypochondriac pain. On evaluation, two isolated hypodense lesions in the spleen were detected. Diagnostic laparoscopy and Splenectomy were performed and histopathology revealed features of primary tubercular abscess. DISCUSSION: Commonly, abdominal visceral involvement is seen as a part of miliary tuberculosis in the immuno-compromised patient. However, in the absence of any co-morbidity and preserved immune function, this case depicts the rare possibility of primary isolated Tubercular splenic abscess in the normal healthy individual. CONCLUSION: We require a close eye and a keen sense of clinical acumen to accurately diagnose and treat smear negative and uncommon forms of Tuberculosis. Considering the growing prevalence and difficulty in disease control, there is need for greater knowledge and awareness to help mitigate the global burden of Tuberculosis. Elsevier 2016-11-25 /pmc/articles/PMC5192240/ /pubmed/28006720 http://dx.doi.org/10.1016/j.ijscr.2016.11.038 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kumar, Suneed
Pai, Ajay G.
Tungenwar, Pravin N.
Bhandarwar, Ajay H.
Isolated primary tuberculosis of spleen—A rare entity in the immuno-competent patient
title Isolated primary tuberculosis of spleen—A rare entity in the immuno-competent patient
title_full Isolated primary tuberculosis of spleen—A rare entity in the immuno-competent patient
title_fullStr Isolated primary tuberculosis of spleen—A rare entity in the immuno-competent patient
title_full_unstemmed Isolated primary tuberculosis of spleen—A rare entity in the immuno-competent patient
title_short Isolated primary tuberculosis of spleen—A rare entity in the immuno-competent patient
title_sort isolated primary tuberculosis of spleen—a rare entity in the immuno-competent patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192240/
https://www.ncbi.nlm.nih.gov/pubmed/28006720
http://dx.doi.org/10.1016/j.ijscr.2016.11.038
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