Chloroquine, an Endocytosis Blocking Agent, Inhibits Zika Virus Infection in Different Cell Models

Zika virus (ZIKV) infection in utero might lead to microcephaly and other congenital defects. Since no specific therapy is available thus far, there is an urgent need for the discovery of agents capable of inhibiting its viral replication and deleterious effects. Chloroquine is widely used as an ant...

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Detalles Bibliográficos
Autores principales: Delvecchio, Rodrigo, Higa, Luiza M., Pezzuto, Paula, Valadão, Ana Luiza, Garcez, Patrícia P., Monteiro, Fábio L., Loiola, Erick C., Dias, André A., Silva, Fábio J. M., Aliota, Matthew T., Caine, Elizabeth A., Osorio, Jorge E., Bellio, Maria, O’Connor, David H., Rehen, Stevens, de Aguiar, Renato Santana, Savarino, Andrea, Campanati, Loraine, Tanuri, Amilcar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192383/
https://www.ncbi.nlm.nih.gov/pubmed/27916837
http://dx.doi.org/10.3390/v8120322

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