Ion Channel Activity of Vpu Proteins Is Conserved throughout Evolution of HIV-1 and SIV

The human immunodeficiency virus type 1 (HIV-1) protein Vpu is encoded exclusively by HIV-1 and related simian immunodeficiency viruses (SIVs). The transmembrane domain of the protein has dual functions: it counteracts the human restriction factor tetherin and forms a cation channel. Since these two...

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Detalles Bibliográficos
Autores principales: Greiner, Timo, Bolduan, Sebastian, Hertel, Brigitte, Groß, Christine, Hamacher, Kay, Schubert, Ulrich, Moroni, Anna, Thiel, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192386/
https://www.ncbi.nlm.nih.gov/pubmed/27916968
http://dx.doi.org/10.3390/v8120325

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