Cargando…

Pharmacokinetics of the Antiviral Lectin Griffithsin Administered by Different Routes Indicates Multiple Potential Uses

Griffithsin (GRFT) is a red alga-derived lectin with demonstrated broad spectrum antiviral activity against enveloped viruses, including severe acute respiratory syndrome–Coronavirus (SARS-CoV), Japanese encephalitis virus (JEV), hepatitis C virus (HCV), and herpes simplex virus-2 (HSV-2). However,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barton, Christopher, Kouokam, J. Calvin, Hurst, Harrell, Palmer, Kenneth E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192392/ https://www.ncbi.nlm.nih.gov/pubmed/27999325 http://dx.doi.org/10.3390/v8120331

Ejemplares similares

Novel Antifungal Activity of Q-Griffithsin, a Broad-Spectrum Antiviral Lectin
por: Nabeta, Henry W., et al.
Publicado: (2021)

Bulk production of the antiviral lectin griffithsin
por: Fuqua, Joshua L., et al.
Publicado: (2015)

Griffithsin: An Antiviral Lectin with Outstanding Therapeutic Potential
por: Lusvarghi, Sabrina, et al.
Publicado: (2016)

Antiviral lectin Q-Griffithsin suppresses fungal infection in murine models of vaginal candidiasis
por: Nabeta, Henry W., et al.
Publicado: (2022)

Studies in a Murine Model Confirm the Safety of Griffithsin and Advocate Its Further Development as a Microbicide Targeting HIV-1 and Other Enveloped Viruses
por: Kouokam, Joseph Calvin, et al.
Publicado: (2016)

Characterization of the hypersensitive response‐like cell death phenomenon induced by targeting antiviral lectin griffithsin to the secretory pathway
por: Kim, Bo Min, et al.
Publicado: (2018)

Investigation of Griffithsin's Interactions with Human Cells Confirms Its Outstanding Safety and Efficacy Profile as a Microbicide Candidate
por: Kouokam, Joseph Calvin, et al.
Publicado: (2011)

Plant-Derived Lectins as Potential Cancer Therapeutics and Diagnostic Tools
por: Mazalovska, Milena, et al.
Publicado: (2020)

Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus
por: Moulaei, Tinoush, et al.
Publicado: (2015)

Low-Cost, Large-Scale Production of the Anti-viral Lectin Griffithsin
por: Decker, John S., et al.
Publicado: (2020)

An algal lectin griffithsin inhibits Hantaan virus infection in vitro and in vivo
por: Zhao, Yajing, et al.
Publicado: (2022)

Lectins as Promising Therapeutics for the Prevention and Treatment of HIV and Other Potential Coinfections
por: Mazalovska, Milena, et al.
Publicado: (2018)

Griffithsin, a Highly Potent Broad-Spectrum Antiviral Lectin from Red Algae: From Discovery to Clinical Application
por: Lee, Choongho
Publicado: (2019)

Domain-Swapped Structure of the Potent Antiviral Protein Griffithsin and Its Mode of Carbohydrate Binding
por: Ziółkowska, Natasza E., et al.
Publicado: (2006)

Improving the large scale purification of the HIV microbicide, griffithsin
por: Fuqua, Joshua L, et al.
Publicado: (2015)

Technoeconomic Modeling of Plant-Based Griffithsin Manufacturing
por: Alam, Aatif, et al.
Publicado: (2018)

Transiently Expressed Mistletoe Lectin II in Nicotiana benthamiana Demonstrates Anticancer Activity In Vitro
por: Mazalovska, Milena, et al.
Publicado: (2020)

Crystallographic studies of the complexes of antiviral protein griffithsin with glucose and N-acetylglucosamine
por: Ziółkowska, Natasza E., et al.
Publicado: (2007)

In vitro antiviral activity of Griffithsin against porcine epidemic diarrhea virus
por: Li, Lan, et al.
Publicado: (2019)

Synergistic anti-HIV-1 activity of griffithsin with tenofovir, maraviroc and enfuvirtide
por: Férir, Geoffrey, et al.
Publicado: (2011)

Grifonin-1: A Small HIV-1 Entry Inhibitor Derived from the Algal Lectin, Griffithsin
por: Micewicz, Ewa D., et al.
Publicado: (2010)

Middle East respiratory syndrome coronavirus infection is inhibited by griffithsin
por: Millet, Jean K., et al.
Publicado: (2016)

Preformulation Characterization of Griffithsin, a Biopharmaceutical Candidate for HIV Prevention
por: Kramzer, Lindsay F., et al.
Publicado: (2021)

Hantavirus Infection Is Inhibited by Griffithsin in Cell Culture
por: Shrivastava-Ranjan, Punya, et al.
Publicado: (2020)

The Antiviral Potential of Algal Lectins
por: Alvarez, Christian, et al.
Publicado: (2023)

In Preparation for Outdoor Pharming: Griffithsin Can Be Expressed in Nicotiana excelsiana and Retains Activity After Storage as Silage
por: Eapen, Paul, et al.
Publicado: (2020)

Sustained Delivery of the Antiviral Protein Griffithsin and Its Adhesion to a Biological Surface by a Silk Fibroin Scaffold
por: Guan, Wenyan, et al.
Publicado: (2023)

Porcine deltacoronavirus infection is inhibited by Griffithsin in cell culture
por: Tang, Rongfeng, et al.
Publicado: (2022)

Pharmacokinetics and Pharmacodynamics of Antibody-Drug Conjugates Administered via Subcutaneous and Intratumoral Routes
por: Chang, Hsuan-Ping, et al.
Publicado: (2023)

Griffithsin and Carrageenan Combination Results in Antiviral Synergy against SARS-CoV-1 and 2 in a Pseudoviral Model
por: Alsaidi, Sahar, et al.
Publicado: (2021)

In vitro Study on Synergistic Interactions Between Free and Encapsulated Q-Griffithsin and Antiretrovirals Against HIV-1 Infection
por: Minooei, Farnaz, et al.
Publicado: (2021)

Pharmacokinetics of Immediate and Sustained Release Cephalexin Administered by Different Routes to Llamas (Lama glama)
por: Kreil, Verónica, et al.
Publicado: (2016)

Development and validation of a product acceptability questionnaire for intranasal Q-Griffithsin COVID-19 prophylaxis (SPRAY PAL)
por: Cash, Elizabeth, et al.
Publicado: (2023)

Griffithsin inhibits Japanese encephalitis virus infection in vitro and in vivo
por: Ishag, Hassan Z. A., et al.
Publicado: (2012)

Lectins and lectibodies: potential promising antiviral agents
por: Nabi-Afjadi, Mohsen, et al.
Publicado: (2022)

Pharmacokinetics of a Novel Sildenafil Orodispersible Film Administered by the Supralingual and the Sublingual Route to Healthy Men
por: Loprete, Luca, et al.
Publicado: (2018)

Griffithsin inhibits porcine reproductive and respiratory syndrome virus infection in vitro
por: Li, Lan, et al.
Publicado: (2018)

Design of Poly(lactic-co-glycolic Acid) (PLGA) Nanoparticles for Vaginal Co-Delivery of Griffithsin and Dapivirine and Their Synergistic Effect for HIV Prophylaxis
por: Yang, Haitao, et al.
Publicado: (2019)

Impact of the griffithsin anti-HIV microbicide and placebo gels on the rectal mucosal proteome and microbiome in non-human primates
por: Girard, Lauren, et al.
Publicado: (2018)

Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus
por: Levendosky, Keith, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_gg2vvl4b50a8n4jbi4fjvtf182