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A Cell Biological Perspective on Past, Present and Future Investigations of the Spindle Assembly Checkpoint
The spindle assembly checkpoint (SAC) is a quality control mechanism that ensures accurate chromosome segregation during cell division. It consists of a mechanochemical signal transduction mechanism that senses the attachment of chromosomes to the spindle, and a signaling cascade that inhibits cell...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192424/ https://www.ncbi.nlm.nih.gov/pubmed/27869759 http://dx.doi.org/10.3390/biology5040044 |