Aldehyde dehydrogenase 2 protects against oxidative stress associated with pulmonary arterial hypertension

The cardioprotective benefits of aldehyde dehydrogenase 2 (ALDH2) are well established, although the regulatory role of ALDH2 in vascular remodeling in pulmonary arterial hypertension (PAH) is largely unknown. ALDH2 potently regulates the metabolism of aldehydes such as 4-hydroxynonenal (4-HNE), the...

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Detalles Bibliográficos
Autores principales: Xu, Tao, Liu, Shuangyue, Ma, Tingting, Jia, Ziyi, Zhang, Zhifei, Wang, Aimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192477/
https://www.ncbi.nlm.nih.gov/pubmed/28030785
http://dx.doi.org/10.1016/j.redox.2016.12.019

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