Cargando…

Achieving HIV-1 Control through RNA-Directed Gene Regulation

HIV-1 infection has been transformed by combined anti-retroviral therapy (ART), changing a universally fatal infection into a controllable infection. However, major obstacles for an HIV-1 cure exist. The HIV latent reservoir, which exists in resting CD4+ T cells, is not impacted by ART, and can reac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klemm, Vera, Mitchell, Jye, Cortez-Jugo, Christina, Cavalieri, Francesca, Symonds, Geoff, Caruso, Frank, Kelleher, Anthony Dominic, Ahlenstiel, Chantelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192495/ https://www.ncbi.nlm.nih.gov/pubmed/27941595 http://dx.doi.org/10.3390/genes7120119

Ejemplares similares

Block and Lock HIV Cure Strategies to Control the Latent Reservoir
por: Ahlenstiel, Chantelle L., et al.
Publicado: (2020)

Controlling HIV-1: Non-Coding RNA Gene Therapy Approaches to a Functional Cure
por: Ahlenstiel, Chantelle L., et al.
Publicado: (2015)

Promoter Targeting RNAs: Unexpected Contributors to the Control of HIV-1 Transcription
por: Suzuki, Kazuo, et al.
Publicado: (2015)

Promoter Targeting shRNA Suppresses HIV-1 Infection In vivo Through Transcriptional Gene Silencing
por: Suzuki, Kazuo, et al.
Publicado: (2013)

The feasibility of incorporating Vpx into lentiviral gene therapy vectors
por: McAllery, Samantha A, et al.
Publicado: (2016)

RNA-induced epigenetic silencing inhibits HIV-1 reactivation from latency
por: Méndez, Catalina, et al.
Publicado: (2018)

Targeted Nanocarrier Delivery of RNA Therapeutics to Control HIV Infection
por: Agbosu, Esinam E., et al.
Publicado: (2022)

Direct evidence of nuclear Argonaute distribution during transcriptional silencing links the actin cytoskeleton to nuclear RNAi machinery in human cells
por: Ahlenstiel, Chantelle L., et al.
Publicado: (2012)

Novel RNA Duplex Locks HIV-1 in a Latent State via Chromatin-mediated Transcriptional Silencing
por: Ahlenstiel, Chantelle, et al.
Publicado: (2015)

The Role of Zinc in Antiviral Immunity
por: Read, Scott A, et al.
Publicado: (2019)

Nanoparticle Delivery Platforms for RNAi Therapeutics Targeting COVID-19 Disease in the Respiratory Tract
por: Zhang, Yuan, et al.
Publicado: (2022)

Nebulization of siRNA for inhalation therapy based on a microfluidic surface acoustic wave platform
por: Cortez-Jugo, Christina, et al.
Publicado: (2022)

The interaction between Epstein–Barr virus and multiple sclerosis genetic risk loci: insights into disease pathogenesis and therapeutic opportunities
por: Afrasiabi, Ali, et al.
Publicado: (2023)

Human papillomavirus in the setting of immunodeficiency: Pathogenesis and the emergence of next-generation therapies to reduce the high associated cancer risk
por: Hewavisenti, Rehana V., et al.
Publicado: (2023)

Stochastic Model of In-Vivo X4 Emergence during HIV Infection: Implications for the CCR5 Inhibitor Maraviroc
por: Savkovic, Borislav, et al.
Publicado: (2012)

Zinc is a potent and specific inhibitor of IFN-λ3 signalling
por: Read, Scott A., et al.
Publicado: (2017)

Engineering of Nebulized Metal–Phenolic Capsules for Controlled Pulmonary Deposition
por: Ju, Yi, et al.
Publicado: (2020)

Direction, Alignment, Commitment: Achieving Better Results Through Leadership
por: McCauley, Cynthia
Publicado: (2015)

Is an HIV vaccine achievable? - Pros
por: Girard, Marc
Publicado: (2014)

Directed Self-Assembly: Expectations and Achievements
por: Kumar, Prashant
Publicado: (2010)

Cholera Cases in Gaya
por: Gupta, Jugo Bondhoo
Publicado: (1897)

Phase I/II Clinical Trials Using Gene-Modified Adult Hematopoietic Stem Cells for HIV: Lessons Learnt
por: Mitsuyasu, Ronald T., et al.
Publicado: (2011)

CCR5 Targeted Cell Therapy for HIV and Prevention of Viral Escape
por: Hütter, Gero, et al.
Publicado: (2015)

The Broad Neutralizing Antibody Responses after HIV-1 Superinfection Are Not Dominated by Antibodies Directed to Epitopes Common in Single Infection
por: Cortez, Valerie, et al.
Publicado: (2015)

Clinical Management of HIV Drug Resistance
por: Cortez, Karoll J., et al.
Publicado: (2011)

The Role of PKC-θ in CD4+ T Cells and HIV Infection: To the Nucleus and Back Again
por: Phetsouphanh, Chansavath, et al.
Publicado: (2015)

Frontloading HIV financing maximizes the achievable impact of HIV prevention
por: Anderson, Sarah‐Jane, et al.
Publicado: (2018)

Interventional Cardiology: Future Directions
por: Kelleher, Mittie E.
Publicado: (1990)

Role of public-private partnerships in achieving UNAIDS HIV treatment targets
por: Shrivastava, Ritu, et al.
Publicado: (2019)

Retroviral Infections in Sheep and Goats: Small Ruminant Lentiviruses and Host Interaction
por: Larruskain, Amaia, et al.
Publicado: (2013)

Finding a cure for HIV: will it ever be achievable?
por: Lewin, Sharon R, et al.
Publicado: (2011)

How Important Are Genes to Achieve Longevity?
por: Caruso, Calogero, et al.
Publicado: (2022)

Explaining the Determinants of First Phase HIV Decay Dynamics through the Effects of Stage-dependent Drug Action
por: Gilmore, James B., et al.
Publicado: (2013)

CCR5 as a Natural and Modulated Target for Inhibition of HIV
por: Burke, Bryan P., et al.
Publicado: (2013)

Direct Integration of the Topological String
por: Grimm, T W, et al.
Publicado: (2007)

Evolution of Cancer Vaccines—Challenges, Achievements, and Future Directions
por: Tay, Ban Qi, et al.
Publicado: (2021)

How U.S. children’s hospitals define population health: a qualitative, interview-based study
por: Skinner, Daniel, et al.
Publicado: (2018)

Achievement and Enhancement
por: Forsberg, Lisa, et al.
Publicado: (2020)

New Communities in Britain—Achievements and Problems
por: Derer, Vera
Publicado: (1962)

A Quantitative Comparison of Anti-HIV Gene Therapy Delivered to Hematopoietic Stem Cells versus CD4+ T Cells
por: Savkovic, Borislav, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_7tm9u1af70hkkbbjkh8v62e3q6