Functions of the RNA Editing Enzyme ADAR1 and Their Relevance to Human Diseases

Adenosine deaminases acting on RNA (ADARs) convert adenosine to inosine in double-stranded RNA (dsRNA). Among the three types of mammalian ADARs, ADAR1 has long been recognized as an essential enzyme for normal development. The interferon-inducible ADAR1p150 is involved in immune responses to both e...

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Detalles Bibliográficos
Autores principales: Song, Chunzi, Sakurai, Masayuki, Shiromoto, Yusuke, Nishikura, Kazuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192505/
https://www.ncbi.nlm.nih.gov/pubmed/27999332
http://dx.doi.org/10.3390/genes7120129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192505/
https://www.ncbi.nlm.nih.gov/pubmed/27999332
http://dx.doi.org/10.3390/genes7120129

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