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Functions of the RNA Editing Enzyme ADAR1 and Their Relevance to Human Diseases
Adenosine deaminases acting on RNA (ADARs) convert adenosine to inosine in double-stranded RNA (dsRNA). Among the three types of mammalian ADARs, ADAR1 has long been recognized as an essential enzyme for normal development. The interferon-inducible ADAR1p150 is involved in immune responses to both e...
Autores principales: | Song, Chunzi, Sakurai, Masayuki, Shiromoto, Yusuke, Nishikura, Kazuko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192505/ https://www.ncbi.nlm.nih.gov/pubmed/27999332 http://dx.doi.org/10.3390/genes7120129 |
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