Gold Nanoparticles for Diagnostics: Advances towards Points of Care

The remarkable physicochemical properties of gold nanoparticles (AuNPs) have prompted developments in the exploration of biomolecular interactions with AuNP-containing systems, in particular for biomedical applications in diagnostics. These systems show great promise in improving sensitivity, ease o...

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Detalles Bibliográficos
Autores principales: Cordeiro, Mílton, Ferreira Carlos, Fábio, Pedrosa, Pedro, Lopez, António, Baptista, Pedro Viana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192518/
https://www.ncbi.nlm.nih.gov/pubmed/27879660
http://dx.doi.org/10.3390/diagnostics6040043
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author Cordeiro, Mílton
Ferreira Carlos, Fábio
Pedrosa, Pedro
Lopez, António
Baptista, Pedro Viana
author_facet Cordeiro, Mílton
Ferreira Carlos, Fábio
Pedrosa, Pedro
Lopez, António
Baptista, Pedro Viana
author_sort Cordeiro, Mílton
collection PubMed
description The remarkable physicochemical properties of gold nanoparticles (AuNPs) have prompted developments in the exploration of biomolecular interactions with AuNP-containing systems, in particular for biomedical applications in diagnostics. These systems show great promise in improving sensitivity, ease of operation and portability. Despite this endeavor, most platforms have yet to reach maturity and make their way into clinics or points of care (POC). Here, we present an overview of emerging and available molecular diagnostics using AuNPs for biomedical sensing that are currently being translated to the clinical setting.
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spelling pubmed-51925182017-01-03 Gold Nanoparticles for Diagnostics: Advances towards Points of Care Cordeiro, Mílton Ferreira Carlos, Fábio Pedrosa, Pedro Lopez, António Baptista, Pedro Viana Diagnostics (Basel) Review The remarkable physicochemical properties of gold nanoparticles (AuNPs) have prompted developments in the exploration of biomolecular interactions with AuNP-containing systems, in particular for biomedical applications in diagnostics. These systems show great promise in improving sensitivity, ease of operation and portability. Despite this endeavor, most platforms have yet to reach maturity and make their way into clinics or points of care (POC). Here, we present an overview of emerging and available molecular diagnostics using AuNPs for biomedical sensing that are currently being translated to the clinical setting. MDPI 2016-11-22 /pmc/articles/PMC5192518/ /pubmed/27879660 http://dx.doi.org/10.3390/diagnostics6040043 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Cordeiro, Mílton
Ferreira Carlos, Fábio
Pedrosa, Pedro
Lopez, António
Baptista, Pedro Viana
Gold Nanoparticles for Diagnostics: Advances towards Points of Care
title Gold Nanoparticles for Diagnostics: Advances towards Points of Care
title_full Gold Nanoparticles for Diagnostics: Advances towards Points of Care
title_fullStr Gold Nanoparticles for Diagnostics: Advances towards Points of Care
title_full_unstemmed Gold Nanoparticles for Diagnostics: Advances towards Points of Care
title_short Gold Nanoparticles for Diagnostics: Advances towards Points of Care
title_sort gold nanoparticles for diagnostics: advances towards points of care
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192518/
https://www.ncbi.nlm.nih.gov/pubmed/27879660
http://dx.doi.org/10.3390/diagnostics6040043
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